TAGS: Plastic Coatings Environmentally Friendly Coatings
Researchers from Middle East Technical University in Turkey showcase a variety of approaches that are alternatives to metallic implants and use natural polymer coatings to improve bone-implant integration, also known as osseointegration.
Implant Surface Modifications
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We utilized a soft structure, which is very similar to human tissues, and placed this structure between human or animal bone and a metal surface,” said author Zafer Evis. “This serves as an interphase increasing bone tendency to attach on implants and prevent loosening or bacterial invasion.”
Establishing a strong and robust chemical interaction between a metal and a completely organic and natural polymer is a significant advancement in the field of bone tissue engineering. It opens a new era of applications with a broader range of modalities that can be applied in almost all hard tissue defects and traumas.
The research showcases several important findings. First, natural polymer coatings significantly improved metal electrochemical corrosion properties, and metals tend to resist corrosion after polymer coating. Second, polysaccharides and proteins can be successfully grafted onto metal surfaces without losing their biological nature.
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One of the surprises is that the coatings can be modified in unlimited ways,” said Evis.
“They can be composited, reconfigured, and tailored to allow or disallow certain biological activities, such as allowing cell attachment while disallowing bacterial attachment.”
Coatings may also be designed to possess multifunctionality, which is the goal in tissue engineering applications. The researchers plan to improve biological functionality of natural polymer coatings on titanium implants. Even though natural polymers can be successfully coated on metal implants, the robustness, yield, and mechanical stability of polymers on metal are still very problematic.
They will try to surpass the need for complex devices and method to improve the stability of polymer-metal interactions and eventually achieve long-term interphase durability. The methods discussed could be used in tandem with other implant surface modification methods to further enhance bioactivity of the metallic implants.
Source: Middle East Technical University