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Cargill and Novozymes to Enable Production of Acrylic Acid Via 3HPA From Renewable Raw Materials

Published on 2008-01-21. Author : SpecialChem

MINNEAPOLIS & COPENHAGEN, Denmark -- Cargill and Novozymes has announced a joint agreement to develop technology enabling the production of acrylic acid via 3-hydroxypropionic acid (3HPA) from renewable raw materials. The project is supported by a $1.5 million matching cooperative agreement from the U.S. Department of Energy.

The collaboration aims at enabling fermentation of sugar into 3HPA using a bioengineered microorganism. The 3HPA can subsequently be transformed into a range of valuable chemical derivatives including acrylic acid -- a high value, high volume chemical that goes into a broad range of materials including plastics, fiber, coatings, paints and super-absorbent diapers.

"Due to increasing oil prices, conversion of renewable raw materials to chemicals is becoming economically viable and holds significant commercial potential," says Novozymes' Executive Vice President Thomas Videbæk, who heads up the company's BioBusiness division. "This strongly positions Novozymes to put its bioinnovation capabilities to work towards our vision of a 'biobased economy' where biomaterials will gradually replace many of the petroleum-based products we know today. The collaboration with Cargill is a good example of how we leverage and build upon our technology base to expand the business into new areas."

Cargill, a leading supplier to the bioindustry globally, already has patents relating to biobased 3HPA. Novozymes will contribute its unique technological platform in protein and pathway engineering, i.e., targeting microorganisms to produce a desired compound. Both companies bring expertise in large-scale fermentation.

"Cargill is already a leading player in the conversion of renewables to chemicals," says Jack Staloch, director of Cargill's BioTechnology Development Center. "Based on the strong Intellectual Property position we've created, we see an opportunity together with Novozymes to make conversion of renewables to 3HPA and its derivatives such as acrylic acid a commercial reality."

The scientific hurdles to be overcome are significant, both companies acknowledge, but they expressed confidence that their combined strengths put them in good positions to tackle the technology challenge. The companies expect the technology to be ready within five years, at which time it will be made available for others to produce and sell 3HPA and its derivatives such as acrylic acid.

Facts About 3HP and Acrylic Acid:

In the process to be developed by Novozymes and Cargill, glucose or another carbohydrate source will be converted to 3-hydroxypropionic acid (3HPA) by fermentation. This conversion is a multi-step enzymatic reaction within the cells of the micro-organism. 3HPA from the fermentation can then be recovered and transformed into chemical derivatives, such as acrylic acid.

At present, the major source of acrylic acid is produced in the petrochemical industry by oxidation of propylene, a product from the refining of crude oil. Almost half of the 3.1 million tons of crude acrylic acid produced annually (2005) is used to make glacial acrylic acid for superabsorbents finding its major use in personal care items such as diapers (more than 1 million tons annually). The remainder is used to produce acrylates that are components of acrylic fibers, coatings, paints and inks.

The acrylic acid market grows approximately 4 percent annually.

About Cargill:

Cargill is an international provider of food, agricultural and risk management products and services. With 158,000 employees in 66 countries, the company is committed to using its knowledge and experience to collaborate with customers to help them succeed.

About Novozymes:

Novozymes is the world leader in bioinnovation. Together with customers across a broad array of industries Novozymes creates tomorrow's industrial biosolutions, improving customers' business and the use of our planet's resources.

Forward-Looking Statements

This release and its related comments contain forward-looking statements. Forward-looking statements are by their very nature associated with risks and uncertainties that may cause actual results to differ materially from expectations. The uncertainties may include such things as unexpected developments in research projects and an unsuccessful collaboration for any reason. The statements in this news release are made as of the date of this release. We undertake no obligation to comment on analyses, expectations or statements made by third parties in respect of Novozymes, its financial or operating results or its securities.

Source: Novozymes


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